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Meng Lv, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Huan Chen, Yuhong Chen, Wei Han, Fengrong Wang, Jingzhi Wang, Kaiyan Liu, Xiaojun Huang, Xiaodong Mo
《医学前沿(英文)》 2019年 第13卷 第6期 页码 667-679 doi: 10.1007/s11684-019-0702-z
关键词: acute graft-versus-host disease chronic graft-versus-host disease National Institutes of Health consensus criteria acute myeloid leukemia anti-thymocyte globulin
免疫调节细胞生物学及其在急性移植物抗宿主病预防或治疗中的临床应用 Review
Bruce R. Blazar
《工程(英文)》 2019年 第5卷 第1期 页码 98-105 doi: 10.1016/j.eng.2018.11.016
预防和治疗移植物抗宿主病(GVHD)最常见的方法是尝试耗竭或抑制能介导或支持同种异体反应的T细胞;但这会导致T细胞受体功能缺陷,并因此对感染和肿瘤复发高度敏感。通常通过广泛使用反应性抗体来实现耗竭,而功能损坏通常在使用需长期给药(一般为6个月或更长时间)且具有明显副作用的药物后发生,这种药物可能不会导致供体T细胞对耐调节方案且携带宿主同种抗原的细胞产生耐受性(即无反应性)。随着对免疫系统稳态认识的深化,我们已能鉴定和表征具有免疫调节功能的细胞群。虽然这种细胞群通常比较少见,但可通过分离和扩增此类细胞的方法在移植后晚期增补供体移植物或进行输注,来抑制GVHD。本文将探讨GVHD模型中的生物学和临床前概念验证,以及现已发展至临床测试阶段的免疫调节细胞疗法对GVHD的疗效。
关键词: 移植物抗宿主病(GVHD) 免疫调节细胞 细胞疗法
Graft versus host disease after liver transplantation: A case report
Peng-Ji GAO, Xi-Sheng LENG, Dong WANG, Guang-Ming LI, Lei HUANG, Jie GAO, JI-Ye ZHU,
《医学前沿(英文)》 2010年 第4卷 第4期 页码 469-472 doi: 10.1007/s11684-010-0120-8
Meng Lv, Yingjun Chang, Xiaojun Huang
《医学前沿(英文)》 2019年 第13卷 第1期 页码 45-56 doi: 10.1007/s11684-017-0595-7
关键词: haploidentical hematopoietic stem cell transplantation conditioning graft-versus-host disease relapse infection donor selection
Quan LI MD , Weiming LI MD , Ping ZOU MD , Jian ZHANG BM ,
《医学前沿(英文)》 2009年 第3卷 第3期 页码 309-315 doi: 10.1007/s11684-009-0043-4
关键词: graft vs host disease proteinase-activated receptor murine model hematopoietic stem cell transplantation
null
《医学前沿(英文)》 2015年 第9卷 第3期 页码 356-360 doi: 10.1007/s11684-015-0404-0
Robotic system has been increasingly used in pancreatectomy. However, the effectiveness of this method remains uncertain. This study compared the surgical outcomes between robot-assisted laparoscopic distal pancreatectomy and conventional laparoscopic distal pancreatectomy. During a 15-year period, 35 patients underwent minimally invasive approach of distal pancreatectomy in our center. Seventeen of these patients had robot-assisted laparoscopic approach, and the remaining 18 had conventional laparoscopic approach. Their operative parameters and perioperative outcomes were analyzed retrospectively in a prospective database. The mean operating time in the robotic group (221.4 min) was significantly longer than that in the laparoscopic group (173.6 min) (P = 0.026). Both robotic and conventional laparoscopic groups presented no significant difference in spleen-preservation rate (52.9% vs. 38.9%) (P = 0.505), operative blood loss (100.3 ml vs. 268.3 ml) (P = 0.29), overall morbidity rate (47.1% vs. 38.9%) (P = 0.73), and post-operative hospital stay (11.4 days vs. 14.2 days) (P = 0.46). Both groups also showed no perioperative mortality. Similar outcomes were observed in robotic distal pancreatectomy and conventional laparoscopic approach. However, robotic approach tended to have the advantages of less blood loss and shorter hospital stay. Further studies are necessary to determine the clinical position of robotic distal pancreatectomy.
关键词: distal pancreatectomy pancreatic neoplasm robotic surgery
Performance and synergistic effect of phenolic and thio antioxidants in ABS graft copolymers
Gongsheng LI, Xuhong GUO, Wang NA, Diancheng HAO, Mingyao ZHANG, Huixuan ZHANG, Jun XU
《化学科学与工程前沿(英文)》 2011年 第5卷 第1期 页码 26-34 doi: 10.1007/s11705-010-0531-8
Hong ZHU, Peiyong QIN
《化学科学与工程前沿(英文)》 2011年 第5卷 第3期 页码 330-338 doi: 10.1007/s11705-010-1104-6
关键词:
(-)-epigallocatechin-3-gallate (EGCG)
tea polyphenols
CDA-
《农业科学与工程前沿(英文)》 2023年 第10卷 第3期 页码 374-389 doi: 10.15302/J-FASE-2023501
● NH3 dispersion from a multi-floor pig building was compared to a single-floor building.
关键词: pig building computational fluid dynamics ammonia dispersion
Integrated analysis of gut microbiome and host immune responses in COVID-19
《医学前沿(英文)》 2022年 第16卷 第2期 页码 263-275 doi: 10.1007/s11684-022-0921-6
Peridynamics versus XFEM: a comparative study for quasi-static crack problems
Jinhai ZHAO, Hesheng TANG, Songtao XUE
《结构与土木工程前沿(英文)》 2018年 第12卷 第4期 页码 548-557 doi: 10.1007/s11709-017-0434-6
关键词: XFEM peridynamic bilateral crack parallel double cracks nonlocal theory
SHI Huangying, CHEN Wenjuan, ZHANG Liming
《化学科学与工程前沿(英文)》 2007年 第1卷 第1期 页码 72-75 doi: 10.1007/s11705-007-0015-7
关键词: transmittance copolymer concentration LCST temperature elemental
Machine perfusion versus cold storage of livers: a meta-analysis
null
《医学前沿(英文)》 2016年 第10卷 第4期 页码 451-464 doi: 10.1007/s11684-016-0474-7
Different organ preservation methods are key factors influencing the results of liver transplantation. In this study, the outcomes of experimental models receiving donation after cardiac death (DCD) livers preserved through machine perfusion (MP) or static cold storage (CS) were compared by conducting a meta-analysis. Standardized mean difference (SMD) and 95% confidence interval (CI) were calculated to compare pooled data from two animal species. Twenty-four studies involving MP preservation were included in the meta-analysis. Compared with CS preservation, MP can reduce the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), and hyaluronic acid (HA) and the changes in liver weight. By contrast, MP can enhance bile production and portal vein flow (PVF). Alkaline phosphatase (ALP) levels and histological changes significantly differed between the two preservation methods. In conclusion, MP of DCD livers is superior to CS in experimental animals.
《农业科学与工程前沿(英文)》 2021年 第8卷 第3期 页码 447-459 doi: 10.15302/J-FASE-2021399
Crop rotations are widely used because they can significantly reduce the incidence of pests and diseases. The interactions between non-host roots and pathogens may be key in the inhibition of soilborne pathogens in crop rotations. Interactions between fennel (Foeniculum vulgare) roots/root exudates and Phytophthora nicotianae were investigated because of the known allelopathy between fennel and tobacco (Nicotiana tabacum). The effects of the key compounds in the fennel rhizosphere on the mycelial growth and zoospore behavior of P. nicotianae were assessed. The roots of fennel attracted P. nicotianae zoospores and inhibited their motility and the germination of cystospores, with some cystospores rupturing. 4-ethylacetophenone, vanillin and N-formylpiperidine were consistently identified in the fennel rhizosphere and were found to interfere with the infection of P. nicotianae, especially vanillin. Hyphae treated with these compounds produced more abnormal branches and accumulated reactive oxygen species. These interspecific interactions between non-host roots and pathogens were found to be an important factor in the inhibition by fennel of infection by P. nicotianae.
关键词: fennel and tobacco rotation infection behavior Phytophthora nicotianae reactive oxygen species vanillin
State versus private sector provision of water services in Armenia
Naira HARUTYUNYAN
《环境科学与工程前沿(英文)》 2012年 第6卷 第5期 页码 620-630 doi: 10.1007/s11783-012-0425-8
关键词: water governance water privatization public-private partnership operational efficiency Armenia transition economy
标题 作者 时间 类型 操作
Risk factors for chronic graft-versus-host disease after anti-thymocyte globulin-based haploidentical
Meng Lv, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Huan Chen, Yuhong Chen, Wei Han, Fengrong Wang, Jingzhi Wang, Kaiyan Liu, Xiaojun Huang, Xiaodong Mo
期刊论文
Graft versus host disease after liver transplantation: A case report
Peng-Ji GAO, Xi-Sheng LENG, Dong WANG, Guang-Ming LI, Lei HUANG, Jie GAO, JI-Ye ZHU,
期刊论文
Everyone has a donor: contribution of the Chinese experience to global practice of haploidentical hematopoietic stem cell transplantation
Meng Lv, Yingjun Chang, Xiaojun Huang
期刊论文
Gene and protein expression of proteinase-activated receptor-1, 2 in a murine model of acute graft hostdisease
Quan LI MD , Weiming LI MD , Ping ZOU MD , Jian ZHANG BM ,
期刊论文
Robotic distal pancreatectomy versus conventional laparoscopic distal pancreatectomy: a comparative study
null
期刊论文
Performance and synergistic effect of phenolic and thio antioxidants in ABS graft copolymers
Gongsheng LI, Xuhong GUO, Wang NA, Diancheng HAO, Mingyao ZHANG, Huixuan ZHANG, Jun XU
期刊论文
Separation of epigallocatechin-3-gallate from crude tea polyphenols by using Cellulose diacetate graft
Hong ZHU, Peiyong QIN
期刊论文
AMMONIA DISPERSION FROM MULTI-FLOOR VERSUS STANDARD SINGLE-FLOOR PIG PRODUCTION FACILITIES BASED ON COMPUTATIONAL
期刊论文
Peridynamics versus XFEM: a comparative study for quasi-static crack problems
Jinhai ZHAO, Hesheng TANG, Songtao XUE
期刊论文
Synthesis and thermosensitive behavior of dextran graft copolymers containing poly (N-vinylcaprolactam
SHI Huangying, CHEN Wenjuan, ZHANG Liming
期刊论文
INTERFERENCE BY NON-HOST PLANT ROOTS AND ROOT EXUDATES IN THE INFECTION PROCESSES OF PHYTOPHTHORA NICOTIANAE
期刊论文